Virtual reality interventions for attention deficit/hyperactivity disorder: a systematic review

Virtual reality (VR) interventions have emerged as innovative approaches increasingly used to manage attention-deficit/hyperactivity disorder (ADHD) in children and adolescents. This systematic review included 22 randomized controlled trials, quasi-experimental, and open-label studies published between 2001 and 2025, comprehensively evaluating the feasibility of VR interventions, their effectiveness alone or combined with pharmacological treatment, the relative efficacy of different training modalities, and dosage-related factors. The results indicate that VR interventions, whether used independently or alongside medication, significantly improve core ADHD symptoms, executive functions, emotional regulation, and social skills, with long-term interventions (≥8 weeks) producing more pronounced and sustained benefits. Among the training modalities, interactive game training was the most frequently studied, followed by virtual scenario and exergaming, each demonstrating distinct effects on cognitive and behavioral outcomes. Overall, VR interventions generally demonstrated high adherence rates; however, adherence reporting was inconsistent across studies, and adverse effects were typically mild and transient. Future research should focus on large-scale randomized controlled trials employing standardized outcome measures and developing personalized VR protocols to further enhance treatment efficacy and clinical applicability for ADHD.

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Publication Details

Journal
npj Digital Medicine
Published
2026-03-03
DOI
https://doi.org/10.1038/s41746-026-02505-9
Primary Topic
Attention Deficit Hyperactivity Disorder
Type
article
Field-Weighted Citation Impact
0.00

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article

Virtual reality interventions for attention deficit/hyperactivity disorder: a systematic review

Charlotte Walton, Yujie Cao, Ningyu Liu, Jiali Wang et al.
npj Digital Medicine
Attention Deficit Hyperactivity Disorder
article

Virtual reality interventions for attention deficit/hyperactivity disorder: a systematic review

Charlotte Walton, Yujie Cao, Ningyu Liu, Jiali Wang, Leilei Ma
article en

Abstract

Virtual reality (VR) interventions have emerged as innovative approaches increasingly used to manage attention-deficit/hyperactivity disorder (ADHD) in children and adolescents. This systematic review included 22 randomized controlled trials, quasi-experimental, and open-label studies published between 2001 and 2025, comprehensively evaluating the feasibility of VR interventions, their effectiveness alone or combined with pharmacological treatment, the relative efficacy of different training modalities, and dosage-related factors. The results indicate that VR interventions, whether used independently or alongside medication, significantly improve core ADHD symptoms, executive functions, emotional regulation, and social skills, with long-term interventions (≥8 weeks) producing more pronounced and sustained benefits. Among the training modalities, interactive game training was the most frequently studied, followed by virtual scenario and exergaming, each demonstrating distinct effects on cognitive and behavioral outcomes. Overall, VR interventions generally demonstrated high adherence rates; however, adherence reporting was inconsistent across studies, and adverse effects were typically mild and transient. Future research should focus on large-scale randomized controlled trials employing standardized outcome measures and developing personalized VR protocols to further enhance treatment efficacy and clinical applicability for ADHD.

npj Digital Medicine
McGovern Institute for Brain Research (US), Beijing Normal University (CN), Chinese Institute for Brain Research (CN), University of Southampton (GB)
National Natural Science Foundation of China, China Postdoctoral Science Foundation, National Science and Technology Major Project, Fundamental Research Funds for the Central Universities
Openalex Percentile: Top 43%
Attention Deficit Hyperactivity Disorder
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