Protective effects of Lagerstroemia speciosa against paracetamol-induced renal and testicular toxicity in rats via antioxidant, anti-inflammatory, and anti-apoptotic mechanisms
Collectively, these findings demonstrate that EELS exerts notable nephroprotective and gonadoprotective effects comparable to NAC, largely through the attenuation of oxidative stress, inflammation, and apoptosis.
Authors
- Rehab M. Bagadood (ORCID: https://orcid.org/0000-0001-5873-4152)
- Mohamed El‐Boshy (ORCID: https://orcid.org/0000-0001-5022-1600)
- Bayan Bokhari
- Bodour S. Rajab (ORCID: https://orcid.org/0000-0002-3874-9434)
- Shaymaa Rezk
- Engy Risha (ORCID: https://orcid.org/0000-0003-1653-1423)
- Ahmed Ateya (ORCID: https://orcid.org/0000-0002-2851-1350)
- Ghadir Sindi
- Nagham E Elsheshtawy
- Fatma Mohamed Abdelhamid
Institutions
- Mansoura University (EG)
- Umm al-Qura University (SA)
- Animal Husbandry and Veterinary Department (IN)
- Department of Animal Husbandry (IN)
Publication Details
- Journal
- Frontiers in Toxicology
- Published
- 2026-03-03
- DOI
- https://doi.org/10.3389/ftox.2026.1751678
- Primary Topic
- Drug-Induced Hepatotoxicity and Protection
- Type
- article
- Field-Weighted Citation Impact
- 0.00