Real-world evidence for atropine titration in myopia control: a comparative study of three low-dose regimens in Chinese children

Low-concentration atropine is effective in controlling myopia progression in children. Among the three concentrations, 0.025% atropine offers better efficacy and tolerability, providing comparable axial elongation control to 0.05% with potentially fewer side effects. These findings support its use as a first-line pharmacologic option for pediatric myopia management in clinical practice.

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Publication Details

Journal
Frontiers in Pharmacology
Published
2026-03-03
DOI
https://doi.org/10.3389/fphar.2026.1716698
Primary Topic
Ophthalmology and Visual Impairment Studies
Type
article
Field-Weighted Citation Impact
0.00
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article

Real-world evidence for atropine titration in myopia control: a comparative study of three low-dose regimens in Chinese children

Hongmei Jiang, Gang Bai, Jianhua Wu, H Li et al.
Frontiers in Pharmacology
Ophthalmology and Visual Impairment Studies
article

Real-world evidence for atropine titration in myopia control: a comparative study of three low-dose regimens in Chinese children

Hongmei Jiang, Gang Bai, Jianhua Wu, H Li, Li Yang, Wenping Qi, Han Zhang, Jian Liu, Dong-Sheng Liang, Gui-Sen Zhang, Peng Wu, Xiao-Ying Wu, Caihan Qiqige, Li-Xin Song
article en

Abstract

Low-concentration atropine is effective in controlling myopia progression in children. Among the three concentrations, 0.025% atropine offers better efficacy and tolerability, providing comparable axial elongation control to 0.05% with potentially fewer side effects. These findings support its use as a first-line pharmacologic option for pediatric myopia management in clinical practice.

Frontiers in PharmacologyVol. 17
Anyang Eye Hospital (CN), Raghudeep Eye Hospital (IN), Chifeng Municipal Hospital (CN)
Openalex Percentile: Top 36%
Ophthalmology and Visual Impairment Studies
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