The role of hypothyroidism in the resilience against depressive episodes during covid pandemic in a cohort of old adults

Older adults generally displayed resilience during the pandemic. However, those with Hypothyroidism experienced increased depressive episodes and worsened quality of life, suggesting reduced stress adaptability despite hormone replacement therapy. This consideration highlights the potential need for interventions addressing both biological and psychosocial factors in managing depression risk in hypothyroid individuals.

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Publication Details

Journal
Frontiers in Psychiatry
Published
2026-03-03
DOI
https://doi.org/10.3389/fpsyt.2026.1603347
Primary Topic
Thyroid Disorders and Treatments
Type
article
Field-Weighted Citation Impact
0.00
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article

The role of hypothyroidism in the resilience against depressive episodes during covid pandemic in a cohort of old adults

Antônio Egídio Nardi, Elisa Cantone, Giulia Cossu, Massimo Tusconi et al.
Frontiers in Psychiatry
Thyroid Disorders and Treatments
article

The role of hypothyroidism in the resilience against depressive episodes during covid pandemic in a cohort of old adults

Antônio Egídio Nardi, Elisa Cantone, Giulia Cossu, Massimo Tusconi, Enzo Tramontano, Stefano Lorrai, Alessandra Perra, Fabrizio Bert, Michela Atzeni, Mauro Giovanni Carta
article en

Abstract

Older adults generally displayed resilience during the pandemic. However, those with Hypothyroidism experienced increased depressive episodes and worsened quality of life, suggesting reduced stress adaptability despite hormone replacement therapy. This consideration highlights the potential need for interventions addressing both biological and psychosocial factors in managing depression risk in hypothyroid individuals.

Frontiers in PsychiatryVol. 17
Universidade Federal do Rio de Janeiro (BR), University of Cagliari (IT), Popular University of Cesar (CO), Klinik für Psychosomatik (DE), Department of Public Health (US)
Good health and well-being
Openalex Percentile: Top 37%
Thyroid Disorders and Treatments
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