Early risk stratification after robot-assisted radical prostatectomy: the role of positive surgical margins

PSMs are associated with an increased risk of early biochemical recurrence, while early functional outcomes appear independent of margin status. Tumor biology, rather than surgical factors, emerges as the main determinant of margin positivity. These findings support a risk-adapted interpretation of PSMs and align with current guidelines favoring close surveillance and early salvage treatment over routine adjuvant therapy.

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Publication Details

Journal
Archivio Italiano di Urologia e Andrologia
Published
2026-03-03
DOI
https://doi.org/10.4081/aiua.2026.14871
Primary Topic
Prostate Cancer Diagnosis and Treatment
Type
article
Field-Weighted Citation Impact
0.00
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article

Early risk stratification after robot-assisted radical prostatectomy: the role of positive surgical margins

M. Arrabal-Martín, María Teresa Melgarejo-Segura, Francisco Gutiérrez-Tejero, A. Zambudio-Munuera et al.
Archivio Italiano di Urologia e Andrologia
Prostate Cancer Diagnosis and Treatment
article

Early risk stratification after robot-assisted radical prostatectomy: the role of positive surgical margins

M. Arrabal-Martín, María Teresa Melgarejo-Segura, Francisco Gutiérrez-Tejero, A. Zambudio-Munuera, Irene Millan-Ramos, Patricia Rodriguez-Parras, Miguel Angel Arrabal-Polo
article en

Abstract

PSMs are associated with an increased risk of early biochemical recurrence, while early functional outcomes appear independent of margin status. Tumor biology, rather than surgical factors, emerges as the main determinant of margin positivity. These findings support a risk-adapted interpretation of PSMs and align with current guidelines favoring close surveillance and early salvage treatment over routine adjuvant therapy.

Archivio Italiano di Urologia e Andrologia
Instituto de Investigación Biosanitaria de Granada (ES)
Openalex Percentile: Top 35%
Prostate Cancer Diagnosis and Treatment
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