GII.23/24/25 noroviruses recognize glycans via a conventional glycan-binding site

Our findings demonstrate that GII.23/24/25 exhibit glycan-binding patterns similar to most other GII HuNoV genotypes. The structural insights provide a better understanding of virus-host evolution and inform the development of therapeutic strategies against HuNoVs.

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Publication Details

Journal
Frontiers in Microbiology
Published
2026-03-03
DOI
https://doi.org/10.3389/fmicb.2026.1767002
Primary Topic
Viral gastroenteritis research and epidemiology
Type
article
Field-Weighted Citation Impact
0.00
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article

GII.23/24/25 noroviruses recognize glycans via a conventional glycan-binding site

Xiaoman Sun, Hanbo Li, Xin Cong, Xinyu Li et al.
Frontiers in Microbiology
Viral gastroenteritis research and epidemiology
article

GII.23/24/25 noroviruses recognize glycans via a conventional glycan-binding site

Xiaoman Sun, Hanbo Li, Xin Cong, Xinyu Li, Jianxun Qi, Zhaojun Duan, Miao Jin
article en

Abstract

Our findings demonstrate that GII.23/24/25 exhibit glycan-binding patterns similar to most other GII HuNoV genotypes. The structural insights provide a better understanding of virus-host evolution and inform the development of therapeutic strategies against HuNoVs.

Frontiers in MicrobiologyVol. 17
South China Agricultural University (CN), Chinese Center For Disease Control and Prevention (CN), Chinese Academy of Sciences (CN), Chengde Medical University (CN), Children's Hospital of Zhejiang University (CN), Czech Academy of Sciences, Institute of Microbiology (CZ), National Institute for Viral Disease Control and Prevention (CN)
Openalex Percentile: Top 36%
Viral gastroenteritis research and epidemiology
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