Targeted and immunotherapy based on tissue of origin in carcinoma of unknown primary: a two-case report and literature review

The two cases reported in this paper demonstrate that targeted and immune treatment plans based on the tissue of origin of the tumor can serve as a clinical option for patients with CUP. These findings may provide new information and references for clinical decision-making in the management of CUP.

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Publication Details

Journal
Frontiers in Oncology
Published
2026-03-03
DOI
https://doi.org/10.3389/fonc.2026.1741467
Primary Topic
Cancer Diagnosis and Treatment
Type
article
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article

Targeted and immunotherapy based on tissue of origin in carcinoma of unknown primary: a two-case report and literature review

Mei Wang, Jingshan Liang, Wen Sun, DongYue Yan
Frontiers in Oncology
Cancer Diagnosis and Treatment
article

Targeted and immunotherapy based on tissue of origin in carcinoma of unknown primary: a two-case report and literature review

Mei Wang, Jingshan Liang, Wen Sun, DongYue Yan
article en

Abstract

The two cases reported in this paper demonstrate that targeted and immune treatment plans based on the tissue of origin of the tumor can serve as a clinical option for patients with CUP. These findings may provide new information and references for clinical decision-making in the management of CUP.

Frontiers in OncologyVol. 16
Xuzhou Medical College (CN), Lianyungang Oriental Hospital (CN), The First People’s Hospital of Lianyungang (CN)
Good health and well-being
Openalex Percentile: Top 34%
Cancer Diagnosis and Treatment
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