Post–myocardial infarction complications in patients with inflammatory bowel disease: a retrospective cohort study using the National Inpatient Sample (2016–2022)

Among 1,456,940 MI hospitalizations, 7,430 had IBD. After adjustment, IBD was associated with higher odds of mortality (aOR 3.32, 95% CI 3.18-3.47; <i>p</i> < 0.0001), left ventricular rupture (aOR 4.46, 95% CI 3.16-6.28; <i>p</i> < 0.0001), left ventricular aneurysm (aOR 1.93, 95% CI 1.61-2.31; <i>p</i> < 0.0001), acute mitral regurgitation (aOR 9.80, 95% CI 6.81-14.10; <i>p</i> < 0.0001), and stent restenosis (aOR 1.16, 95% CI 1.07-1.26; <i>p</i> = 0.0002). IBD was also associated with longer hospital stay (coefficient 2.13 days, 95% CI 2.03-2.23; <i>p</i> < 0.0001) and higher total hospital charges.Conclusion: IBD was associated with worse in-hospital outcomes and higher resource utilization after MI in this nationwide hospitalization-level analysis.