Trichosporon asahii infection in a lower limb stump: A diagnostic challenge in a severely burned patient

<i>Trichosporon asahii</i> is an opportunistic yeast that colonizes the skin and mucous membranes but may cause severe invasive infections in critically ill patients. We report the case of an 81-year old man with extensive second- and third degree thermal burns (30-39% total body surface area) who, during the third week of intensive care, developed a deep infection of a previously amputated femoral stump. Cultures repeatedly yielded multidrug-resistant <i>Pseudomonas aeruginosa</i> and <i>T. asahii</i>, identified by MALDI-TOF mass spectrometry. Combined surgical management and antimicrobial therapy with meropenem and posaconazole led to clinical resolution and a favourable outcome.