Analysis of factors influencing retinal thickness in chronic obstructive pulmonary disease and hypertension: a cross-sectional study in a community-dwelling middle-aged and elderly population

COPD and hypertension are independent risk factors for changes in retinal thickness, with heterogeneous effects across different retinal regions. DBP, but not SBP, independently correlates with inner retinal thickness, and antihypertensive therapy mitigates this effect to specific regions. These findings provide new insights for community ocular screening and retinal protection in hypertensive patients.

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Publication Details

Journal
Frontiers in Medicine
Published
2026-03-03
DOI
https://doi.org/10.3389/fmed.2026.1752515
Primary Topic
Retinal Diseases and Treatments
Type
article
Field-Weighted Citation Impact
0.00

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article

Analysis of factors influencing retinal thickness in chronic obstructive pulmonary disease and hypertension: a cross-sectional study in a community-dwelling middle-aged and elderly population

Zhongqi Wan, Ruoyi Lin, Meijiang Zhu, Donghui Yu et al.
Frontiers in Medicine
Retinal Diseases and Treatments
article

Analysis of factors influencing retinal thickness in chronic obstructive pulmonary disease and hypertension: a cross-sectional study in a community-dwelling middle-aged and elderly population

Zhongqi Wan, Ruoyi Lin, Meijiang Zhu, Donghui Yu, Ren CD, Yue Wu, Wenting Cai, Tianyi Shen, Jing Yu, Chengyu Hu, Tingting Li
article en

Abstract

COPD and hypertension are independent risk factors for changes in retinal thickness, with heterogeneous effects across different retinal regions. DBP, but not SBP, independently correlates with inner retinal thickness, and antihypertensive therapy mitigates this effect to specific regions. These findings provide new insights for community ocular screening and retinal protection in hypertensive patients.

Frontiers in MedicineVol. 13
Tongji University (CN), Second Military Medical University (CN), Sichuan University (CN), Renji Hospital (CN), West China Hospital of Sichuan University (CN), Shanghai Eye Disease Prevention & Treatment Center (CN), Changhai Hospital (CN), Pudong Medical Center (CN), Shanghai East Hospital (CN), Shanghai Tenth People's Hospital (CN), Tongji Hospital (CN)
Fundamental Research Funds for the Central Universities
Good health and well-being
Openalex Percentile: Top 35%
Retinal Diseases and Treatments
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Analysis of factors influencing retinal thickness in chronic obstructive pulmonary disease and hypertension: a cross-sectional study in a community-dwelling middle-aged and elderly population — Zhongqi Wan, Ruoyi Lin, et al. · Frontiers in Medicine (2026) | TGRS Research Map | TGRS