Donor-derived cell-free DNA in combination with liver function tests for biopsy decision-making in pediatric liver transplantation
In this large pediatric study, we demonstrate for the first time that low dd-cfDNA levels can reliably identify liver transplant patients at low risk of rejection, improving the tailoring of surveillance biopsies when used alongside LFTs.
Authors
- Julia Minetto (ORCID: https://orcid.org/0009-0005-5467-2720)
- S. Conde
- Florencia D’Arielli
- Daniel G. Maluf (ORCID: https://orcid.org/0000-0002-5921-4834)
- Leandro Lauferman (ORCID: https://orcid.org/0000-0002-4160-3647)
- Oscar Imventarza
- Agustina Jacobo Dillon
- Marcelo Dip
- Diego Aredes
- Hayellen Reijenstein
- Débora Chan (ORCID: https://orcid.org/0009-0005-3765-2947)
- Guido Trezeguet Renatti (ORCID: https://orcid.org/0009-0006-6149-4085)
- Paula Schaiquevich (ORCID: https://orcid.org/0000-0002-2568-4731)
- Andrea Bosaleh
- Natalia Riva (ORCID: https://orcid.org/0000-0001-8359-4040)
- Santiago Cervio
- Catalina Costas
- Andres Farall
- Agostina Arrigone
- Esteban Halac
- María Teresa García de Dávila
- Gabriela Aboud (ORCID: https://orcid.org/0009-0003-1521-0369)
- Florencia Degrave
- Ivone Malla
- Sílvia Casas
Institutions
- University of Maryland, Baltimore (US)
- CARE USA (US)
- Austral University (AR)
- Garrahan Hospital (AR)
- Centro Científico Tecnológico - San Juan (AR)
- Exact Sciences (United States) (US)
- Fundación para la Investigación, Docencia y Prevención del Cáncer (AR)
- University of Maryland, College Park (US)
Publication Details
- Journal
- Liver Transplantation
- Published
- 2026-03-02
- DOI
- https://doi.org/10.1097/lvt.0000000000000848
- Primary Topic
- Organ Transplantation Techniques and Outcomes
- Type
- article
- Field-Weighted Citation Impact
- 0.00