Open-source modular field-programmable gate array system for two-photon mesoscope enabling multiarea, multidepth neural activity recording and lifetime imaging

This modular, open-source FPGA + CDP system increases throughput of large-FOV two-photon imaging and adds lifetime contrast without specialized lasers, facilitating multiscale <i>in vivo</i> studies and broad biomedical applications.

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Publication Details

Journal
Neurophotonics
Published
2026-03-03
DOI
https://doi.org/10.1117/1.nph.13.1.015013
Primary Topic
Photochromic and Fluorescence Chemistry
Type
article
Field-Weighted Citation Impact
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article

Open-source modular field-programmable gate array system for two-photon mesoscope enabling multiarea, multidepth neural activity recording and lifetime imaging

Kazuto Kobayashi, Hidehiko Takahashi, Takehisa Handa, Spencer L. Smith et al.
Neurophotonics
Photochromic and Fluorescence Chemistry
article

Open-source modular field-programmable gate array system for two-photon mesoscope enabling multiarea, multidepth neural activity recording and lifetime imaging

Kazuto Kobayashi, Hidehiko Takahashi, Takehisa Handa, Spencer L. Smith, Y. Yoneyama, Che-Hang Yu, Akihiro Funamizu, Hiroki Shiwaku, Riichiro Hira, Reiko Hira, Yoshikazu Isomura, Atsushi Kamoshida, Fumiya Imamura, Hiroto Imamura, Shigeki Kato
article en

Abstract

This modular, open-source FPGA + CDP system increases throughput of large-FOV two-photon imaging and adds lifetime contrast without specialized lasers, facilitating multiscale <i>in vivo</i> studies and broad biomedical applications.

NeurophotonicsVol. 13(01)
Tokyo Medical and Dental University (JP), Fukushima Medical University (JP), University of California, Santa Barbara (US), Saitama Institute of Technology (JP), TiGenix (Spain) (ES), Quantitative BioSciences (US), Kyocera (Japan) (JP), Institute of Behavioral Sciences (JP)
Openalex Percentile: Top 38%
Photochromic and Fluorescence Chemistry
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Open-source modular field-programmable gate array system for two-photon mesoscope enabling multiarea, multidepth neural activity recording and lifetime imaging — Kazuto Kobayashi, Hidehiko Takahashi, et al. · Neurophotonics (2026) | TGRS Research Map | TGRS