Acute transfusion reactions in sub‐Saharan Africa: A systematic review and meta‐analysis

ATRs are common in SSA and are strongly associated with the use of whole blood. The broader implementation of blood component therapy could substantially reduce their burden. Central to ATR prevention in the region are strengthening pre-transfusion evaluation and testing, expanding leukoreduction, establishing robust in-hospital haemovigilance systems and promoting appropriate blood use.

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Publication Details

Journal
Vox Sanguinis
Published
2026-03-02
DOI
https://doi.org/10.1111/vox.70203
Primary Topic
Blood transfusion and management
Type
article
Field-Weighted Citation Impact
0.00
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article

Acute transfusion reactions in sub‐Saharan Africa: A systematic review and meta‐analysis

Henk Schonewille, Stephen Twumasi, Lilian Antwi Boateng
Vox Sanguinis
Blood transfusion and management
article

Acute transfusion reactions in sub‐Saharan Africa: A systematic review and meta‐analysis

Henk Schonewille, Stephen Twumasi, Lilian Antwi Boateng
article en

Abstract

ATRs are common in SSA and are strongly associated with the use of whole blood. The broader implementation of blood component therapy could substantially reduce their burden. Central to ATR prevention in the region are strengthening pre-transfusion evaluation and testing, expanding leukoreduction, establishing robust in-hospital haemovigilance systems and promoting appropriate blood use.

Vox Sanguinis
Kwame Nkrumah University of Science and Technology (GH), Sanquin (NL), Cégep de l'Outaouais (CA)
Good health and well-being
Openalex Percentile: Top 39%
Blood transfusion and management
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