A comprehensive evaluation of non-vascular prepontine cistern anatomy influencing trigeminal nerve vulnerability using machine learning-based morphometric analysis
Non-vascular morphometric variation in the prepontine cistern, particularly at the porus level nerve caliber, Meckel cave size, and sagittal angle, contributes to TN pathophysiology. An AI-assisted, leakage-free morphometry pipeline yields reproducible and interpretable discrimination, supporting the integration of vascular and non-vascular anatomy into diagnostic and treatment planning workflows.
Authors
- Gökalp Tulum (ORCID: https://orcid.org/0000-0003-1906-0401)
- Ömer Karadaş (ORCID: https://orcid.org/0000-0003-0457-3722)
- Muhammet İkbal IŞIK (ORCID: https://orcid.org/0000-0002-2132-8457)
- Akçay Övünç Karadaş
- Onur Osman
- Necibe Sare Mert
- Zehra Şimşek
- Berza Özcan
- Tuba Baldan Ağaoğlu
- Ferhat Cüce
- Niray Baş
Institutions
- Istanbul University (TR)
- University of Health Sciences Antigua (AG)
Publication Details
- Journal
- Frontiers in Medicine
- Published
- 2026-03-03
- DOI
- https://doi.org/10.3389/fmed.2026.1745815
- Primary Topic
- Trigeminal Neuralgia and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00