Comparative efficacy of non-pharmacological interventions for post-stroke cognitive impairment: a systematic review and network meta-analysis of randomized controlled trials

Among non-pharmacological approaches for PSCI, combined CCT and tDCS produced the most consistent cognitive improvements, while tDCS and exercise rehabilitation yielded the most pronounced gains in functional recovery. These findings support the clinical integration of multimodal brain stimulation and cognitive rehabilitation strategies in the management of PSCI.

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Publication Details

Journal
Frontiers in Neurology
Published
2026-03-03
DOI
https://doi.org/10.3389/fneur.2026.1644663
Primary Topic
Stroke Rehabilitation and Recovery
Type
article
Field-Weighted Citation Impact
0.00
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article

Comparative efficacy of non-pharmacological interventions for post-stroke cognitive impairment: a systematic review and network meta-analysis of randomized controlled trials

Weili Li, Lidong Du, Xin Zheng, Jun Luo et al.
Frontiers in Neurology
Stroke Rehabilitation and Recovery
article

Comparative efficacy of non-pharmacological interventions for post-stroke cognitive impairment: a systematic review and network meta-analysis of randomized controlled trials

Weili Li, Lidong Du, Xin Zheng, Jun Luo, Xiujuan Yang, Jin Liang, Hongmei Niu
article en

Abstract

Among non-pharmacological approaches for PSCI, combined CCT and tDCS produced the most consistent cognitive improvements, while tDCS and exercise rehabilitation yielded the most pronounced gains in functional recovery. These findings support the clinical integration of multimodal brain stimulation and cognitive rehabilitation strategies in the management of PSCI.

Frontiers in NeurologyVol. 17
Minzu University of China (CN), State Ethnic Affairs Commission (CN), Gansu University of Traditional Chinese Medicine (CN), Integrated Chinese Medicine (China) (HK), Gansu Provincial Hospital (CN), Shandong Provincial QianFoShan Hospital (CN), Shandong First Medical University (CN)
Openalex Percentile: Top 36%
Stroke Rehabilitation and Recovery
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