D-SFANet: Application of a Multimodal Fusion Framework Based on Attention Mechanisms in ADHD Identification and Classification

The diagnosis of attention-deficit/hyperactivity disorder (ADHD) has long relied on subjective scales, lacking objective neuroimaging biomarkers. Static functional connectivity (sFC) and dynamic functional connectivity (dFC), as commonly used metrics in resting-state functional magnetic resonance imaging (rs-fMRI) analysis, provide important perspectives for related research. However, existing unimodal approaches struggle to effectively integrate the spatiotemporal characteristics of functional connectivity. To address this, this paper proposes the multimodal fusion framework D-SFANet, which synergistically models the static and dynamic features of brain functional connectivity through an attention mechanism: in the static path, it integrates a multi-scale convolutional network with phenotypic information extraction to extract hierarchical topological features; in the dynamic path, it combines graph theory with a bidirectional long short-term memory network (BiLSTM) to capture key state transition patterns in brain networks. Experimental validation demonstrates that D-SFANet achieves significantly higher classification accuracy than existing mainstream methods, robustly validating the effectiveness of its spatiotemporal fusion strategy.

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Publication Details

Journal
Mathematics
Published
2026-03-02
DOI
https://doi.org/10.3390/math14050851
Primary Topic
Functional Brain Connectivity Studies
Type
article
Field-Weighted Citation Impact
0.00

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article

D-SFANet: Application of a Multimodal Fusion Framework Based on Attention Mechanisms in ADHD Identification and Classification

Ming Jing, Guangcheng Dongye, Li Zhang
Mathematics
Functional Brain Connectivity Studies
article

D-SFANet: Application of a Multimodal Fusion Framework Based on Attention Mechanisms in ADHD Identification and Classification

Ming Jing, Guangcheng Dongye, Li Zhang
article en

Abstract

The diagnosis of attention-deficit/hyperactivity disorder (ADHD) has long relied on subjective scales, lacking objective neuroimaging biomarkers. Static functional connectivity (sFC) and dynamic functional connectivity (dFC), as commonly used metrics in resting-state functional magnetic resonance imaging (rs-fMRI) analysis, provide important perspectives for related research. However, existing unimodal approaches struggle to effectively integrate the spatiotemporal characteristics of functional connectivity. To address this, this paper proposes the multimodal fusion framework D-SFANet, which synergistically models the static and dynamic features of brain functional connectivity through an attention mechanism: in the static path, it integrates a multi-scale convolutional network with phenotypic information extraction to extract hierarchical topological features; in the dynamic path, it combines graph theory with a bidirectional long short-term memory network (BiLSTM) to capture key state transition patterns in brain networks. Experimental validation demonstrates that D-SFANet achieves significantly higher classification accuracy than existing mainstream methods, robustly validating the effectiveness of its spatiotemporal fusion strategy.

MathematicsVol. 14(5)
Qilu University of Technology (CN), Shandong Women’s University (CN)
Texas Space Grant Consortium, National Natural Science Foundation of China
Openalex Percentile: Top 39%
Functional Brain Connectivity Studies
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D-SFANet: Application of a Multimodal Fusion Framework Based on Attention Mechanisms in ADHD Identification and Classification — Ming Jing, Guangcheng Dongye, et al. · Mathematics (2026) | TGRS Research Map | TGRS