Trends in central precocious puberty incidence in Japan during the COVID-19 pandemic

This multicenter study demonstrates a significant increase in CPP incidence among girls during the COVID-19 pandemic in Japan, with sustained elevation in the post-pandemic period. Although clinical characteristics remained largely unchanged, the consistently higher degree of overweight underscores the need to consider lifestyle and environmental factors that may have been exacerbated during the pandemic. Ongoing surveillance and reevaluation of CPP diagnostic criteria may be warranted to address emerging epidemiological trends.

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Publication Details

Journal
Frontiers in Pediatrics
Published
2026-03-03
DOI
https://doi.org/10.3389/fped.2026.1769902
Primary Topic
Hypothalamic control of reproductive hormones
Type
article
Field-Weighted Citation Impact
0.00
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article

Trends in central precocious puberty incidence in Japan during the COVID-19 pandemic

Koji Ohsugi, Yosuke Komatsu, Kuniyuki Nishiyama, Nobuyuki Kikuchi et al.
Frontiers in Pediatrics
Hypothalamic control of reproductive hormones
article

Trends in central precocious puberty incidence in Japan during the COVID-19 pandemic

Koji Ohsugi, Yosuke Komatsu, Kuniyuki Nishiyama, Nobuyuki Kikuchi, Kentaro Shiga
article en

Abstract

This multicenter study demonstrates a significant increase in CPP incidence among girls during the COVID-19 pandemic in Japan, with sustained elevation in the post-pandemic period. Although clinical characteristics remained largely unchanged, the consistently higher degree of overweight underscores the need to consider lifestyle and environmental factors that may have been exacerbated during the pandemic. Ongoing surveillance and reevaluation of CPP diagnostic criteria may be warranted to address emerging epidemiological trends.

Frontiers in PediatricsVol. 14
Yokohama City University Medical Center (JP), Kanagawa Children's Medical Center (JP), Odawara Municipal Hospital (JP), Japan Organization of Occupational Health and Safety (JP), National Hospital Organization (JP), Yokohama City University (JP)
Good health and well-being
Openalex Percentile: Top 32%
Hypothalamic control of reproductive hormones
DOIOpen Access PDFOpenAlex
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Trends in central precocious puberty incidence in Japan during the COVID-19 pandemic — Koji Ohsugi, Yosuke Komatsu, et al. · Frontiers in Pediatrics (2026) | TGRS Research Map | TGRS