Anti-Inflammatory and Synaptic Protective Effects of TNF-α Inactivation in the MDX Mouse Model
Together, our findings indicate that TNF-α blockade by Etanercept exerts neuroprotective and anti-inflammatory actions in the spinal cord of dystrophic mice, providing new insights into the impact of TNF-α signaling on neuroinflammatory processes in DMD.
Authors
- Alexandre Leite Rodrigues de Oliveira (ORCID: https://orcid.org/0000-0003-4224-4575)
- Valquíria Aparecida Matheus (ORCID: https://orcid.org/0000-0001-8528-8004)
- Ana Laura Midori Rossi Tomiyama
- Anna Oller Bonani
Institutions
- Universidade Estadual de Campinas (UNICAMP) (BR)
Publication Details
- Journal
- Current Issues in Molecular Biology
- Published
- 2026-03-03
- DOI
- https://doi.org/10.3390/cimb48030270
- Primary Topic
- Muscle Physiology and Disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Fundação de Amparo à Pesquisa do Estado de São Paulo
- Coordenação de Aperfeiçoamento de Pessoal de Nível Superior
- Conselho Nacional de Desenvolvimento Científico e Tecnológico
- Universidade Estadual de Campinas