Associations Between Prenatal Cannabis Exposure and Birth Outcomes: Results from a Prospective Cohort Study

Prenatal cannabis exposure was associated with reduced birthweight and SGA in this cohort. Nicotine co-exposure intensified these associations, yet effects persisted without cotinine, supporting cannabis as an independent perinatal risk factor and emphasizing the value of cotinine assessment in populations where blunt use or secondhand exposure is common.

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Publication Details

Journal
medRxiv
Published
2026-03-03
DOI
https://doi.org/10.64898/2026.03.01.26347369
Primary Topic
Cannabis and Cannabinoid Research
Type
article
Field-Weighted Citation Impact
0.00

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article

Associations Between Prenatal Cannabis Exposure and Birth Outcomes: Results from a Prospective Cohort Study

Anna M. Constantino-Pettit, Ryan Bogdan, Cassie Trammel, Ebony Carter et al.
medRxiv
Cannabis and Cannabinoid Research
article

Associations Between Prenatal Cannabis Exposure and Birth Outcomes: Results from a Prospective Cohort Study

Anna M. Constantino-Pettit, Ryan Bogdan, Cassie Trammel, Ebony Carter, Arpana Agrawal, Christopher Smyser
article en

Abstract

Prenatal cannabis exposure was associated with reduced birthweight and SGA in this cohort. Nicotine co-exposure intensified these associations, yet effects persisted without cotinine, supporting cannabis as an independent perinatal risk factor and emphasizing the value of cotinine assessment in populations where blunt use or secondhand exposure is common.

medRxiv
University of North Carolina at Chapel Hill (US), Washington University in St. Louis (US), Society for Maternal-Fetal Medicine (US)
National Institute of Mental Health
Good health and well-being
Openalex Percentile: Top 36%
Cannabis and Cannabinoid Research
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