Epidemiology of gastrointestinal stroma tumours (GIST) in Germany 2003 – 2021: Rising incidence and improved survival

In line with national and international data, the incidence of GIST in Germany increased between 2003 and 2021, while survival has improved in the same time period after the introduction of imatinib for adjuvant treatment of GIST in Germany in the year 2009. An increasing number of small endoscopically detected lesions may have contributed to the rising incidence of GIST. Primary care physicians should be aware of the increasing frequency of GIST. With the collection of detailed therapy data and information on prognostic markers, further evaluations of clinical issues will also be possible in the future using German cancer registry data.

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Publication Details

Journal
Cancer Epidemiology
Published
2026-03-03
DOI
https://doi.org/10.1016/j.canep.2026.103039
Primary Topic
Gastrointestinal Tumor Research and Treatment
Type
article
Field-Weighted Citation Impact
0.00
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article

Epidemiology of gastrointestinal stroma tumours (GIST) in Germany 2003 – 2021: Rising incidence and improved survival

Jens Jakob, Sylke Zeissig, Martin Radespiel-Tröger, Peter Hohenberger et al.
Cancer Epidemiology
Gastrointestinal Tumor Research and Treatment
article

Epidemiology of gastrointestinal stroma tumours (GIST) in Germany 2003 – 2021: Rising incidence and improved survival

Jens Jakob, Sylke Zeissig, Martin Radespiel-Tröger, Peter Hohenberger, Jacqueline Müller-Nordhorn
article en

Abstract

In line with national and international data, the incidence of GIST in Germany increased between 2003 and 2021, while survival has improved in the same time period after the introduction of imatinib for adjuvant treatment of GIST in Germany in the year 2009. An increasing number of small endoscopically detected lesions may have contributed to the rising incidence of GIST. Primary care physicians should be aware of the increasing frequency of GIST. With the collection of detailed therapy data and information on prognostic markers, further evaluations of clinical issues will also be possible in the future using German cancer registry data.

Cancer EpidemiologyVol. 102
Heidelberg University (DE), University Hospital Heidelberg (DE), Health and Safety Authority (IE), University Medical Centre Mannheim (DE)
Good health and well-being
Openalex Percentile: Top 35%
Gastrointestinal Tumor Research and Treatment
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