Impact of ketamine infusions on healthcare utilization and chronic pain: a comparative effectiveness study with insights from real-world data

IV ketamine was more effective than conventional therapy in reducing unexpected pain-related healthcare utilization for over 6 months in patients with chronic pain. Our study highlights the value of using real-world data and comparative effectiveness research to supplement clinical trials and enhance our understanding of the possible effects of outpatient ketamine infusion therapy.

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Publication Details

Journal
Regional Anesthesia & Pain Medicine
Published
2026-03-03
DOI
https://doi.org/10.1136/rapm-2025-106975
Primary Topic
Treatment of Major Depression
Type
article
Field-Weighted Citation Impact
0.00
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article

Impact of ketamine infusions on healthcare utilization and chronic pain: a comparative effectiveness study with insights from real-world data

Suzanne Labriola, Ajay D. Wasan, Brian O’Connell, Trent Emerick et al.
Regional Anesthesia & Pain Medicine
Treatment of Major Depression
article

Impact of ketamine infusions on healthcare utilization and chronic pain: a comparative effectiveness study with insights from real-world data

Suzanne Labriola, Ajay D. Wasan, Brian O’Connell, Trent Emerick, Rebecca Shue DeSensi, Michael J Lynch, Sheri Wang
article en

Abstract

IV ketamine was more effective than conventional therapy in reducing unexpected pain-related healthcare utilization for over 6 months in patients with chronic pain. Our study highlights the value of using real-world data and comparative effectiveness research to supplement clinical trials and enhance our understanding of the possible effects of outpatient ketamine infusion therapy.

Regional Anesthesia & Pain Medicine
University of Pittsburgh (US)
Openalex Percentile: Top 36%
Treatment of Major Depression
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