Patient comorbidities, medication intake, and mortality in revision surgery for periprosthetic joint infection of the hip and knee: analysis of 346 patients

Patients undergoing revision surgery for PJI after total hip and knee arthroplasty show an increased in-hospital mortality in the presence of the following comorbidities: dementia, renal insufficiency, and history of malignancy. Based on the present results, further infection prevention and geriatric co-management strategies should be evaluated for patients undergoing revision arthroplasty of the hip and knee for PJI.

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Publication Details

Journal
Journal of Orthopaedic Surgery and Research
Published
2026-03-03
DOI
https://doi.org/10.1186/s13018-025-06209-w
Primary Topic
Orthopedic Infections and Treatments
Type
article
Field-Weighted Citation Impact
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article

Patient comorbidities, medication intake, and mortality in revision surgery for periprosthetic joint infection of the hip and knee: analysis of 346 patients

Ulf Krister Hofmann, Andreas Bell, Vanessa Poth, Tommaso Bardazzi et al.
Journal of Orthopaedic Surgery and Research
Orthopedic Infections and Treatments
article

Patient comorbidities, medication intake, and mortality in revision surgery for periprosthetic joint infection of the hip and knee: analysis of 346 patients

Ulf Krister Hofmann, Andreas Bell, Vanessa Poth, Tommaso Bardazzi, Michael Celik, Arne Driessen, Christian David Weber, Frank Hildebrand, Nicola Maffulli, Marcel Betsch, Filippo Migliorini
article en

Abstract

Patients undergoing revision surgery for PJI after total hip and knee arthroplasty show an increased in-hospital mortality in the presence of the following comorbidities: dementia, renal insufficiency, and history of malignancy. Based on the present results, further infection prevention and geriatric co-management strategies should be evaluated for patients undergoing revision arthroplasty of the hip and knee for PJI.

Journal of Orthopaedic Surgery and ResearchVol. 21(1)
Queen Mary University of London (GB), Mile End Hospital (GB), Universitätsklinikum Erlangen (DE), Ospedale di Bolzano (IT), Luisenhospital Aachen (DE), Schmerzklinik Kiel (DE), Health & Life (Taiwan) (TW), Keele University (GB), Martin Luther University Halle-Wittenberg (DE), Sapienza University of Rome (IT), Immersion (United States) (US), RWTH Aachen University (DE)
Good health and well-being
Openalex Percentile: Top 36%
Orthopedic Infections and Treatments
DOIOpen Access PDFOpenAlex
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Patient comorbidities, medication intake, and mortality in revision surgery for periprosthetic joint infection of the hip and knee: analysis of 346 patients — Ulf Krister Hofmann, Andreas Bell, et al. · Journal of Orthopaedic Surgery and Research (2026) | TGRS Research Map | TGRS