A systematic review comparing sex-specific outcomes of prospective clinical trials and subsequent real-world data focusing on systemic treatment options for renal cell cancer

This systematic review enlightens sex-specific gaps in enrollment and cancer outcome, as well as the lack of sex-specific toxicity analyses. Balanced enrollment rates and reporting of sex-specific toxicity should be obligate in evaluations of la/mRCC treatments.

Authors

Publication Details

Journal
Urologia Internationalis
Published
2026-03-03
DOI
https://doi.org/10.1159/000551236
Primary Topic
Renal cell carcinoma treatment
Type
article
Field-Weighted Citation Impact
0.00

Funders

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article

A systematic review comparing sex-specific outcomes of prospective clinical trials and subsequent real-world data focusing on systemic treatment options for renal cell cancer

Axel S. Merseburger, Lara Franziska Stolzenbach, Nils Gilbert, Lea Sophie Lütje et al.
Urologia Internationalis
Renal cell carcinoma treatment
article

A systematic review comparing sex-specific outcomes of prospective clinical trials and subsequent real-world data focusing on systemic treatment options for renal cell cancer

Axel S. Merseburger, Lara Franziska Stolzenbach, Nils Gilbert, Lea Sophie Lütje, Friederike Praus, Daniar Osmonov, Marie Christine Roesch
article en

Abstract

This systematic review enlightens sex-specific gaps in enrollment and cancer outcome, as well as the lack of sex-specific toxicity analyses. Balanced enrollment rates and reporting of sex-specific toxicity should be obligate in evaluations of la/mRCC treatments.

Urologia Internationalis
Amgen, Bristol-Myers Squibb, Pfizer, AstraZeneca, Sanofi, Teva Pharmaceutical Industries, Eisai, Astellas Pharma, Ipsen
Good health and well-being
Openalex Percentile: Top 36%
Renal cell carcinoma treatment
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