ALKBH5 promotes ovarian cancer progression by activating Notch2 signaling

In summary, our findings demonstrated that ALKBH5 promotes the progression of ovarian cancer by activating Notch2 signaling, and suggested that ALKBH5 functions as an oncogene and may serve as a prognostic biomarker and therapeutic target in ovarian cancer.

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Publication Details

Journal
Biological Procedures Online
Published
2026-03-03
DOI
https://doi.org/10.1186/s12575-026-00330-8
Primary Topic
TGF-β signaling in diseases
Type
article
Field-Weighted Citation Impact
0.00
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article

ALKBH5 promotes ovarian cancer progression by activating Notch2 signaling

Luhong Li, Cong Peng, Qian Wang, Yanying Liu et al.
Biological Procedures Online
TGF-β signaling in diseases
article

ALKBH5 promotes ovarian cancer progression by activating Notch2 signaling

Luhong Li, Cong Peng, Qian Wang, Yanying Liu, Hao Liu, Huafeng Luo, Ziao Gao, Ruiyun Wu
article en

Abstract

In summary, our findings demonstrated that ALKBH5 promotes the progression of ovarian cancer by activating Notch2 signaling, and suggested that ALKBH5 functions as an oncogene and may serve as a prognostic biomarker and therapeutic target in ovarian cancer.

Biological Procedures Online
Fujian Medical University (CN), Second Affiliated Hospital of Fujian Medical University (CN), Guangzhou Medical University Cancer Hospital (CN), Guangzhou Medical University (CN)
Zero hunger
Openalex Percentile: Top 36%
TGF-β signaling in diseases
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