Neurodevelopmental outcomes of infants born at high altitude: evidence from Tibet

This is the first prospective cohort study to compare the neurodevelopmental outcomes of high-altitude born/raised infants with those of low-altitude controls. Infants born and raised at high-altitude exhibited lower neurodevelopmental scores and a higher likelihood of failing in the gross motor domain of ASQ-3. High-altitude exposure had no negative influence on infants' physical growth and other neurodevelopmental domains assessed by the ASQ-3.

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Publication Details

Journal
Pediatric Research
Published
2026-03-03
DOI
https://doi.org/10.1038/s41390-026-04821-y
Primary Topic
Neonatal and fetal brain pathology
Type
article
Field-Weighted Citation Impact
0.00

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article

Neurodevelopmental outcomes of infants born at high altitude: evidence from Tibet

Ouzhu Luobu, Duoji Luosang, Zhang Qy, Xi Liu et al.
Pediatric Research
Neonatal and fetal brain pathology
article

Neurodevelopmental outcomes of infants born at high altitude: evidence from Tibet

Ouzhu Luobu, Duoji Luosang, Zhang Qy, Xi Liu, Wenbin Zhang, Ming Li, Xueting Gao, Shanshan Meng, Qunpei Zhaxi, Kejun Du, Qian Dong, Xiaoming Chen, Siyao Zeng, Yang Zhou
article en

Abstract

This is the first prospective cohort study to compare the neurodevelopmental outcomes of high-altitude born/raised infants with those of low-altitude controls. Infants born and raised at high-altitude exhibited lower neurodevelopmental scores and a higher likelihood of failing in the gross motor domain of ASQ-3. High-altitude exposure had no negative influence on infants' physical growth and other neurodevelopmental domains assessed by the ASQ-3.

Pediatric Research
Northwest Women's and Children's Hospital (CN), Guangdong Province Women and Children Hospital (CN), Air Force Medical University (CN)
National Science Foundation, National Natural Science Foundation of China
Good health and well-being
Openalex Percentile: Top 36%
Neonatal and fetal brain pathology
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