Synergistic action of human milk oligosaccharides and lactoferrin enhances neurodevelopment in piglets: evidence from MRS based metabolic profiling

The combined cHMOs and Lf supplementation may synergistically support neurodevelopment by enhancing lipid mobilization, energy metabolism, and antioxidant capacity, while cHMOs alone promotes brain development by improving neuronal integrity and synaptic activity in piglets - a translational model for human infants. To our knowledge, these findings have not been previously reported.

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Publication Details

Journal
Nutritional Neuroscience
Published
2026-03-02
DOI
https://doi.org/10.1080/1028415x.2026.2637610
Primary Topic
Infant Nutrition and Health
Type
article
Field-Weighted Citation Impact
0.00
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article

Synergistic action of human milk oligosaccharides and lactoferrin enhances neurodevelopment in piglets: evidence from MRS based metabolic profiling

Adikari Arachchige Dilki Indrachapa Adikari, Z. Chen, Xiaoming Zheng, M. Amin et al.
Nutritional Neuroscience
Infant Nutrition and Health
article

Synergistic action of human milk oligosaccharides and lactoferrin enhances neurodevelopment in piglets: evidence from MRS based metabolic profiling

Adikari Arachchige Dilki Indrachapa Adikari, Z. Chen, Xiaoming Zheng, M. Amin, T. Amin, Bing Wang
article en

Abstract

The combined cHMOs and Lf supplementation may synergistically support neurodevelopment by enhancing lipid mobilization, energy metabolism, and antioxidant capacity, while cHMOs alone promotes brain development by improving neuronal integrity and synaptic activity in piglets - a translational model for human infants. To our knowledge, these findings have not been previously reported.

Nutritional Neuroscience
Charles Sturt University (AU), Australian Regenerative Medicine Institute (AU), Monash University (AU)
Openalex Percentile: Top 36%
Infant Nutrition and Health
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