Single-cell analysis of TIGD genes in hepatocellular carcinoma: Prognostic value and functional characterization
TIGD4, TIGD5, and TIGD6 exhibit oncogenic potential and may serve as prognostic biomarkers and therapeutic targets in HCC. Their stem-cell-associated expression highlights a novel connection between transposable element-derived genes and liver cancer stemness.
Authors
- Baoding Li
- Jing Liu (ORCID: https://orcid.org/0009-0001-5132-7236)
- Chengwei Yang
- Xiaopeng Chen
- Cheng Liu
Institutions
- Sun Yat-sen University (CN)
- Ningxia Medical University (CN)
- Third Affiliated Hospital of Sun Yat-sen University (CN)
- The Fourth People's Hospital of Ningxia Hui Autonomous Region (CN)
Publication Details
- Journal
- Translational Oncology
- Published
- 2026-03-02
- DOI
- https://doi.org/10.1016/j.tranon.2026.102722
- Primary Topic
- Cancer Cells and Metastasis
- Type
- article
- Field-Weighted Citation Impact
- 0.00