The predictive value of surrogate insulin resistance indices for T2DM complicated with metabolic syndrome: a retrospective study based on hospitalized patients in China

The surrogate indices for IR (the TyG index, the TyG-BMI index, and the TG/HDL-C ratio) were risk factors for T2DM complicated with MetS, among which the TG/HDL-C ratio was the optimal predictor. The nomogram model constructed based on the TG/HDL-C ratio, Sex, WHR, and FCP demonstrated good predictive performance for T2DM complicated with MetS. This model shows good calibration and practicality, providing a valuable reference to aid in early identification and preventive strategies in clinical practice.

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Publication Details

Journal
Frontiers in Endocrinology
Published
2026-03-02
DOI
https://doi.org/10.3389/fendo.2026.1782071
Primary Topic
Diabetes, Cardiovascular Risks, and Lipoproteins
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article
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article

The predictive value of surrogate insulin resistance indices for T2DM complicated with metabolic syndrome: a retrospective study based on hospitalized patients in China

Xi Zhang, Jianbin Sun, Sixu Xin, Xin Zhao
Frontiers in Endocrinology
Diabetes, Cardiovascular Risks, and Lipoproteins
article

The predictive value of surrogate insulin resistance indices for T2DM complicated with metabolic syndrome: a retrospective study based on hospitalized patients in China

Xi Zhang, Jianbin Sun, Sixu Xin, Xin Zhao
article en

Abstract

The surrogate indices for IR (the TyG index, the TyG-BMI index, and the TG/HDL-C ratio) were risk factors for T2DM complicated with MetS, among which the TG/HDL-C ratio was the optimal predictor. The nomogram model constructed based on the TG/HDL-C ratio, Sex, WHR, and FCP demonstrated good predictive performance for T2DM complicated with MetS. This model shows good calibration and practicality, providing a valuable reference to aid in early identification and preventive strategies in clinical practice.

Frontiers in EndocrinologyVol. 17
Peking University (CN), Peking University International Hospital (CN)
Reduced inequalities
Openalex Percentile: Top 37%
Diabetes, Cardiovascular Risks, and Lipoproteins
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