Emergent laparoscopic pancreatectomy with splenectomy for a primary pancreatic lymphoma with spontaneous splenic rupture: a case report

Primary pancreatic lymphoma (PPL), which is defined as lymphoma originating from pancreatic lymphoid tissue or infiltrating lymphocytes, is a rare clinical manifestation with non - specific symptoms. Surgical resection is not regarded as the first - line treatment for PPL; however, it may be indicated for the management of complications or the clarification of diagnosis in challenging cases. Emergent laparocospic distal pancreatectomy with splenectomy (E-LDPS) has not been reported to treat emergent conditions of PPL. Herein, a 63 - year - old male who underwent emergency laparotomy due to acute intra - abdominal hemorrhage is presented. Intraoperative findings led to a radical LDPS due to suspected splenic rupture. Subsequently, histopathological examination confirmed primary diffuse large B - cell lymphoma of the pancreas. The patient completed a full - course chemotherapy regimen and achieved complete remission, with no recurrence observed during the follow - up period. This case highlights the potential significance of early minimally invasive surgical intervention in the management of PPL when emergent complications occur in high volume center.

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Publication Details

Journal
Journal of Pancreatology
Published
2026-03-02
DOI
https://doi.org/10.1097/jp9.0000000000000253
Primary Topic
Pancreatic and Hepatic Oncology Research
Type
article
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article

Emergent laparoscopic pancreatectomy with splenectomy for a primary pancreatic lymphoma with spontaneous splenic rupture: a case report

Zhe Cao, Qiaofei Liu, Hua Huang, Lin Cong
Journal of Pancreatology
Pancreatic and Hepatic Oncology Research
article

Emergent laparoscopic pancreatectomy with splenectomy for a primary pancreatic lymphoma with spontaneous splenic rupture: a case report

Zhe Cao, Qiaofei Liu, Hua Huang, Lin Cong
article en

Abstract

Primary pancreatic lymphoma (PPL), which is defined as lymphoma originating from pancreatic lymphoid tissue or infiltrating lymphocytes, is a rare clinical manifestation with non - specific symptoms. Surgical resection is not regarded as the first - line treatment for PPL; however, it may be indicated for the management of complications or the clarification of diagnosis in challenging cases. Emergent laparocospic distal pancreatectomy with splenectomy (E-LDPS) has not been reported to treat emergent conditions of PPL. Herein, a 63 - year - old male who underwent emergency laparotomy due to acute intra - abdominal hemorrhage is presented. Intraoperative findings led to a radical LDPS due to suspected splenic rupture. Subsequently, histopathological examination confirmed primary diffuse large B - cell lymphoma of the pancreas. The patient completed a full - course chemotherapy regimen and achieved complete remission, with no recurrence observed during the follow - up period. This case highlights the potential significance of early minimally invasive surgical intervention in the management of PPL when emergent complications occur in high volume center.

Journal of Pancreatology
Chinese Academy of Medical Sciences & Peking Union Medical College (CN), Peking Union Medical College Hospital (CN)
Good health and well-being
Openalex Percentile: Top 35%
Pancreatic and Hepatic Oncology Research
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Emergent laparoscopic pancreatectomy with splenectomy for a primary pancreatic lymphoma with spontaneous splenic rupture: a case report — Zhe Cao, Qiaofei Liu, et al. · Journal of Pancreatology (2026) | TGRS Research Map | TGRS