Diagnostic Test Accuracy and Semi-Quantitative Metrics of 18F-FDG PET in Assessing Treatment Response in Skull Base Osteomyelitis and Necrotising Otitis Externa: A Systematic Review and Meta-Analysis

<sup>18</sup>F-FDG PET, specifically using SUVmax, demonstrates high sensitivity and good specificity for treatment response monitoring, with excellent capacity to rule out persistent infection. However, evidence quality is limited by retrospective designs and substantial heterogeneity. Prospective studies with standardised thresholds are needed to validate clinical utility.

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Publication Details

Journal
Tomography
Published
2026-03-02
DOI
https://doi.org/10.3390/tomography12030032
Primary Topic
Ear Surgery and Otitis Media
Type
article
Field-Weighted Citation Impact
0.00

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article

Diagnostic Test Accuracy and Semi-Quantitative Metrics of 18F-FDG PET in Assessing Treatment Response in Skull Base Osteomyelitis and Necrotising Otitis Externa: A Systematic Review and Meta-Analysis

Jean‐Marc Gérard, Sukanya Rajiv, Maya Reid, Mark Laidlaw
Tomography
Ear Surgery and Otitis Media
article

Diagnostic Test Accuracy and Semi-Quantitative Metrics of 18F-FDG PET in Assessing Treatment Response in Skull Base Osteomyelitis and Necrotising Otitis Externa: A Systematic Review and Meta-Analysis

Jean‐Marc Gérard, Sukanya Rajiv, Maya Reid, Mark Laidlaw
article en

Abstract

<sup>18</sup>F-FDG PET, specifically using SUVmax, demonstrates high sensitivity and good specificity for treatment response monitoring, with excellent capacity to rule out persistent infection. However, evidence quality is limited by retrospective designs and substantial heterogeneity. Prospective studies with standardised thresholds are needed to validate clinical utility.

TomographyVol. 12(3)
Cochlear (Australia) (AU), The University of Melbourne (AU), University of Canberra (AU), The Royal Victorian Eye & Ear Hospital (AU), Act Health (AU)
Australian Society of Otolaryngology Head and Neck Surgery
Good health and well-being
Openalex Percentile: Top 35%
Ear Surgery and Otitis Media
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Diagnostic Test Accuracy and Semi-Quantitative Metrics of 18F-FDG PET in Assessing Treatment Response in Skull Base Osteomyelitis and Necrotising Otitis Externa: A Systematic Review and Meta-Analysis — Jean‐Marc Gérard, Sukanya Rajiv, et al. · Tomography (2026) | TGRS Research Map | TGRS