Risk factors for major gastrointestinal bleeding in septic patients: a multicenter retrospective study

Although MGB occurred in only 2.0% of septic patients, it was associated with substantially higher mortality. Older age, renal dysfunction, elevated BUN and gastrointestinal sources were key drivers of risk, while urinary tract infection was associated with a lower risk. These findings underscore the importance of early risk stratification and targeted preventive strategies in high-risk patients to mitigate bleeding events and improve survival.

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Publication Details

Journal
Scandinavian Journal of Gastroenterology
Published
2026-03-02
DOI
https://doi.org/10.1080/00365521.2026.2636063
Primary Topic
Sepsis Diagnosis and Treatment
Type
article
Field-Weighted Citation Impact
0.00
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article

Risk factors for major gastrointestinal bleeding in septic patients: a multicenter retrospective study

L. Zhang, Heng Zhang, Liang Zhang, Yi Zhang et al.
Scandinavian Journal of Gastroenterology
Sepsis Diagnosis and Treatment
article

Risk factors for major gastrointestinal bleeding in septic patients: a multicenter retrospective study

L. Zhang, Heng Zhang, Liang Zhang, Yi Zhang, Yuanyuan Feng, Yang Li
article en

Abstract

Although MGB occurred in only 2.0% of septic patients, it was associated with substantially higher mortality. Older age, renal dysfunction, elevated BUN and gastrointestinal sources were key drivers of risk, while urinary tract infection was associated with a lower risk. These findings underscore the importance of early risk stratification and targeted preventive strategies in high-risk patients to mitigate bleeding events and improve survival.

Scandinavian Journal of Gastroenterology
Army Medical University (CN), Shanghai Jiao Tong University (CN), Ruijin Hospital (CN), Daping Hospital (CN), Chongqing Emergency Medical Center (CN), Huazhong University of Science and Technology (CN)
Good health and well-being
Openalex Percentile: Top 37%
Sepsis Diagnosis and Treatment
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