Macrophage-derived CCL20 promotes abdominal aortic aneurysm progression via lymphocytes CCR6
Macrophage-derived CCL20 aggravates lymphocyte recruitment via the CCR6, promoting AAA progression. CCL20 may serve as a biomarker for AAA. Targeting the CCL20-CCR6 axis could inhibit immune recruitment and AAA progression.
Authors
- Dachuan Guo
- Qingnan Ren
- Wencheng Zhang (ORCID: https://orcid.org/0000-0003-3730-5361)
- Jianjun Jiang (ORCID: https://orcid.org/0000-0002-6722-1268)
- Yang Zhao (ORCID: https://orcid.org/0000-0003-1444-5927)
- Qi He
- Hao Bai
- FengXin Wan
- Ke Xiao
- Mengfan Zhi
- Tianyong Sun
- Xiangjiu Ding
- Yuanbin Cao
- Song Shen
- Ping Sui
- Li Wei
Institutions
- Shandong University (CN)
- Qilu Hospital of Shandong University (CN)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2026-03-02
- DOI
- https://doi.org/10.3389/fimmu.2026.1780720
- Primary Topic
- Aortic aneurysm repair treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00