Impact of prehospital antibiotic therapy differs depending on septic shock origin
The prehospital antibiotics administration is associated with a reduced risk of 30-day mortality among patients suffering from septic shock cared for by a prehospital MICU. The prehospital antibiotic treatment effect differs according to septic shock origin. However, prospective studies are necessary to validate these preliminary findings and to assess the supplementary effects of the bundle of care components.
Authors
- Vincent Bounes
- Josiane Boularan
- Emmanuel Bloch-Laine
- Vincent Garrouste (ORCID: https://orcid.org/0000-0003-0936-4831)
- Basile Gilbert
- Benoit Vivien
- Patrick Ecollan
- Romain Jouffroy
- Daniel Jost
- Papa Gueye
Institutions
- Université d'Orléans (FR)
- Inserm (FR)
- Université Fédérale de Toulouse Midi-Pyrénées (FR)
- Université Paris-Saclay (FR)
- Brigade des Sapeurs Pompiers de Paris (FR)
- Service de Santé des Armées (FR)
- Sorbonne Université (FR)
- Hôpital Cochin (FR)
- Centre de recherche en Epidémiologie et Santé des Populations (FR)
- Centre Hospitalier Intercommunal Castres-Mazamet (FR)
- Pitié-Salpêtrière Hospital (FR)
- Centre Hospitalier Universitaire de Martinique (MQ)
- Centre hospitalier universitaire d'Orléans (FR)
- Institut National du Sport, de l'Expertise et de la Performance (FR)
Publication Details
- Journal
- Journal of Intensive Care
- Published
- 2026-03-02
- DOI
- https://doi.org/10.1186/s40560-026-00853-y
- Primary Topic
- Sepsis Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00