Genome-Wide Association Analysis of Pathologies in Piglets of Landrace and Large White Breeds

A genome-wide association study is conducted to identify gene polymorphisms in pigs associated with common pathologies in young animals. The genomes of 97 pigs (Landrace and Large White breeds) are sequenced, followed by genome-wide association analysis to identify possible markers of potentially heritable defects (malnutrition, gastroenteritis, scrotal hernia and cryptorchidism, tremors at birth). Polymorphisms are found in various genes, including those associated with development of the nervous system and the formation of neurological diseases, even in the case of pathologies not directly related to the functions of the nervous system.

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Publication Details

Journal
Nanobiotechnology Reports
Published
2025-12-01
DOI
https://doi.org/10.1134/s2635167625601652
Primary Topic
Genetic Mapping and Diversity in Plants and Animals
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article
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article

Genome-Wide Association Analysis of Pathologies in Piglets of Landrace and Large White Breeds

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article

Genome-Wide Association Analysis of Pathologies in Piglets of Landrace and Large White Breeds

A. A. Frolova, A. E. Sazonov, A. V. Prokopenko, M. V. Patrushev, V. S. Bezuglov, S. S. Bulanov, A. A. Borisova, E. D. Solovkova
article en

Abstract

A genome-wide association study is conducted to identify gene polymorphisms in pigs associated with common pathologies in young animals. The genomes of 97 pigs (Landrace and Large White breeds) are sequenced, followed by genome-wide association analysis to identify possible markers of potentially heritable defects (malnutrition, gastroenteritis, scrotal hernia and cryptorchidism, tremors at birth). Polymorphisms are found in various genes, including those associated with development of the nervous system and the formation of neurological diseases, even in the case of pathologies not directly related to the functions of the nervous system.

Nanobiotechnology ReportsVol. 20(6)
National Research Tomsk State University (RU), Kurchatov Institute (RU)
Zero hunger
Openalex Percentile: Top 20%
Genetic Mapping and Diversity in Plants and Animals
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