A refined approach of the tachypacing porcine model of heart failure
We established a reliable model of tachypacing-induced HF based on slower pacing and milder progression to HF, while reducing the stress and suffering of the animals.
Authors
- Jens Ötvös
- Alessandro Faragli (ORCID: https://orcid.org/0000-0003-0883-2672)
- Alessio Alogna (ORCID: https://orcid.org/0000-0001-5988-2720)
- Francesco Paolo Lo Muzio (ORCID: https://orcid.org/0000-0002-4730-2458)
- Leonhard Berboth (ORCID: https://orcid.org/0000-0002-4896-2095)
- Gianluigi Longinotti-Buitoni
- Philipp Attanasio (ORCID: https://orcid.org/0000-0002-6559-7499)
- Heiner Post
- Burkert Pieske (ORCID: https://orcid.org/0000-0002-6144-4380)
- Paul Steendijk
- Frank Heinzel
- Beatrice De Marchi
Institutions
- Leiden University Medical Center (NL)
- Deutsches Herzzentrum der Charité (DE)
- E I L (China) (CN)
- German Centre for Cardiovascular Research (DE)
- Berlin Institute of Health at Charité - Universitätsmedizin Berlin (DE)
- Franklin University (US)
- Charité - Universitätsmedizin Berlin (DE)
Publication Details
- Journal
- Frontiers in Cardiovascular Medicine
- Published
- 2026-03-02
- DOI
- https://doi.org/10.3389/fcvm.2026.1726438
- Primary Topic
- Cardiomyopathy and Myosin Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Deutsche Forschungsgemeinschaft
- Berlin Institute of Health
- Horizon 2020 Framework Programme