Invasive stratified mucin-producing carcinoma of the cervix: a report of 34 cases of immunohistochemical and clinicopathological findings
The proportion of mixed ISMC cases is similar to that of pure ISMC. ISMC is more aggressive compared to HPV-associated endocervical adenocarcinoma and is associated with shorter progression-free survival. We recommend the following markers as a diagnostic panel for ISMC: p16, CK7, CK5/6, P40, P63, Pax-8, and PAS.
Authors
- Lianbao Cao
- Ting Hao (ORCID: https://orcid.org/0000-0003-4667-4556)
- Ru Wang (ORCID: https://orcid.org/0000-0002-2768-1753)
- Danyang Zhao (ORCID: https://orcid.org/0000-0001-8219-0300)
- Ming Liu
- Hao Yu
- Songsheng Zhang
Institutions
- Qingdao University (CN)
- Academy of Medical Sciences (GB)
- Shandong Tumor Hospital (CN)
- Shandong Maternal and Child Health Hospital (CN)
- Shandong First Medical University (CN)
- Qingdao Women and Children's Hospital (CN)
Publication Details
- Journal
- Frontiers in Oncology
- Published
- 2026-03-02
- DOI
- https://doi.org/10.3389/fonc.2026.1681399
- Primary Topic
- Endometrial and Cervical Cancer Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00