Finerenone is associated with pronounced uric acid reduction in hyperuricemic diabetic kidney disease: a real-world analysis

In this real-world cohort, finerenone use was associated with significant reductions in albuminuria and SUA, particularly among patients with hyperuricemia. These findings suggest a potential dual benefit in this high-risk subgroup and highlight the importance of baseline SUA in interpreting finerenone's metabolic effects. The observed SUA reduction warrants further prospective investigation.

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Publication Details

Journal
Frontiers in Pharmacology
Published
2026-03-02
DOI
https://doi.org/10.3389/fphar.2026.1782658
Primary Topic
Gout, Hyperuricemia, Uric Acid
Type
article
Field-Weighted Citation Impact
0.00
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article

Finerenone is associated with pronounced uric acid reduction in hyperuricemic diabetic kidney disease: a real-world analysis

Yanmei Lin, Jianqing Tian, Kang Du, Bo Liu
Frontiers in Pharmacology
Gout, Hyperuricemia, Uric Acid
article

Finerenone is associated with pronounced uric acid reduction in hyperuricemic diabetic kidney disease: a real-world analysis

Yanmei Lin, Jianqing Tian, Kang Du, Bo Liu
article en

Abstract

In this real-world cohort, finerenone use was associated with significant reductions in albuminuria and SUA, particularly among patients with hyperuricemia. These findings suggest a potential dual benefit in this high-risk subgroup and highlight the importance of baseline SUA in interpreting finerenone's metabolic effects. The observed SUA reduction warrants further prospective investigation.

Frontiers in PharmacologyVol. 17
Union Hospital (HK), Southern Company (United States) (US), First Affiliated Hospital of Xiamen University (CN)
Good health and well-being
Openalex Percentile: Top 44%
Gout, Hyperuricemia, Uric Acid
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