Construction and validation of a prognostic model for lung adenocarcinoma based on necrotic cell death triggered by sodium overload-related coexpressed genes

The findings provide new molecular markers and potential therapeutic targets for the prognosis of LUAD and lay a theoretical foundation for the development of therapeutic approaches targeting the NECSO mechanism in patients with LUAD.

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Publication Details

Journal
Frontiers in Genetics
Published
2026-03-02
DOI
https://doi.org/10.3389/fgene.2026.1763705
Primary Topic
Ferroptosis and cancer prognosis
Type
article
Field-Weighted Citation Impact
0.00

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article

Construction and validation of a prognostic model for lung adenocarcinoma based on necrotic cell death triggered by sodium overload-related coexpressed genes

Quan Zhu, Ting Huang, Chunjing Chen, Xiaoqi Chen et al.
Frontiers in Genetics
Ferroptosis and cancer prognosis
article

Construction and validation of a prognostic model for lung adenocarcinoma based on necrotic cell death triggered by sodium overload-related coexpressed genes

Quan Zhu, Ting Huang, Chunjing Chen, Xiaoqi Chen, Fangguo LU, Li Liang, Huihui Liu
article en

Abstract

The findings provide new molecular markers and potential therapeutic targets for the prognosis of LUAD and lay a theoretical foundation for the development of therapeutic approaches targeting the NECSO mechanism in patients with LUAD.

Frontiers in GeneticsVol. 17
Hunan University of Traditional Chinese Medicine (CN)
National Natural Science Foundation of China, Hunan University, Natural Science Foundation of Hunan Province, Hunan University of Chinese Medicine
Good health and well-being
Openalex Percentile: Top 36%
Ferroptosis and cancer prognosis
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