Label-free fluorescence lifetime imaging for rapid discrimination of high-grade prostate cancer in fresh biopsy cores: a feasibility study
FLIm demonstrates strong potential for identifying high-grade PCa. Because measurements were performed using a single fiber optic, this approach can be readily integrated into standard prostate biopsy devices to enable FLIm-guided and real-time tissue characterization during the biopsy procedure and to inform targeted tissue collection.
Authors
- Jinyi Qi
- Laura Marcu
- Xiangnan Zhou
- Yash Tipirneni
- Shuai Chen
- Marc Dall’Era
- Julien Bec
- Kenneth A. Iczkowski
Institutions
- University of California Davis Medical Center (US)
- University of California, Davis (US)
Publication Details
- Journal
- Journal of Biomedical Optics
- Published
- 2026-03-02
- DOI
- https://doi.org/10.1117/1.jbo.31.3.036001
- Primary Topic
- Advanced Fluorescence Microscopy Techniques
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Institutes of Health
- University of California, Davis
- National Cancer Institute
- Comprehensive Cancer Center, University of California, Davis