Genetic and phenotypic characterization of the plasmid-encoded NDM-80 metallo-β-lactamase in Escherichia coli isolated from a pediatric patient

This study is the first to report on the emergence of the <i>bla</i> <sub><i>NDM-</i>80</sub> variant, shedding light on its functional mechanism. Our findings enrich the repertoire of NDM resistance genes and highlight the need for increased surveillance of pathogens harboring <i>bla</i> <sub><i>NDM</i></sub> variants.

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Journal
Frontiers in Microbiology
Published
2026-03-02
DOI
https://doi.org/10.3389/fmicb.2026.1770791
Primary Topic
Antibiotic Resistance in Bacteria
Type
article
Field-Weighted Citation Impact
0.00

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article

Genetic and phenotypic characterization of the plasmid-encoded NDM-80 metallo-β-lactamase in Escherichia coli isolated from a pediatric patient

Jinlan Zhou, Qimeng Fan, Qing Meng, Fupin Hu et al.
Frontiers in Microbiology
Antibiotic Resistance in Bacteria
article

Genetic and phenotypic characterization of the plasmid-encoded NDM-80 metallo-β-lactamase in Escherichia coli isolated from a pediatric patient

Jinlan Zhou, Qimeng Fan, Qing Meng, Fupin Hu, Li Ding, Gangfeng Yan, Weiwei Yang, Guoping Lu, Yan Guo
article en

Abstract

This study is the first to report on the emergence of the <i>bla</i> <sub><i>NDM-</i>80</sub> variant, shedding light on its functional mechanism. Our findings enrich the repertoire of NDM resistance genes and highlight the need for increased surveillance of pathogens harboring <i>bla</i> <sub><i>NDM</i></sub> variants.

Frontiers in MicrobiologyVol. 17
Fudan University (CN), National Health and Family Planning Commission (CN), Ministry of Health of the Russian Federation (RU), Drug Discovery Laboratory (Norway) (NO), Shenzhen Children's Hospital (CN), Children's Hospital of Fudan University (CN), Huashan Hospital (CN)
National Natural Science Foundation of China
Openalex Percentile: Top 36%
Antibiotic Resistance in Bacteria
DOIOpen Access PDFOpenAlex
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Genetic and phenotypic characterization of the plasmid-encoded NDM-80 metallo-β-lactamase in Escherichia coli isolated from a pediatric patient — Jinlan Zhou, Qimeng Fan, et al. · Frontiers in Microbiology (2026) | TGRS Research Map | TGRS