Association of Brain Network Perturbations With Response to Vagus Nerve Stimulation in Children With Drug-Resistant Focal Epilepsy
Our results provide evidence that connectivity of an intrinsic, anterior-dominant network is associated with response to VNS. Responders to VNS are characterized by stronger baseline connectivity of this network and greater resilience of this network to IED-related disruption.
Authors
- Suna Jung
- Karim Mithani (ORCID: https://orcid.org/0000-0002-8094-3070)
- Sebastian C. Coleman (ORCID: https://orcid.org/0000-0001-7868-2839)
- Puneet Jain (ORCID: https://orcid.org/0000-0002-6420-4999)
- Hrishikesh Suresh (ORCID: https://orcid.org/0000-0003-0412-5655)
- Simeon M. Wong (ORCID: https://orcid.org/0000-0001-9070-0665)
- Ayako Ochi
- Vann Chau
- Lauren Sham
- George M. Ibrahim
- S. Weiss
- Manuela Mohareb
- Stephanie Ann Holowka
- Elizabeth J. Donner
- Hiroshi Otsubo
- James T. Rutka
Institutions
- University of Toronto (CA)
- Toronto Rehabilitation Institute (CA)
- Hospital for Sick Children (CA)
Publication Details
- Journal
- Neurology
- Published
- 2026-03-02
- DOI
- https://doi.org/10.1212/wnl.0000000000214710
- Primary Topic
- Vagus Nerve Stimulation Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00