Effects of manual acupuncture on microglial polarization and the Sirt1/NF-κB pathway in a rat model of post-stroke depression
MA promoted the transformation of microglia from M1 to M2 in the prefrontal lobe of PSD rats, reduces the inflammatory response and improves depression-like behavior in rats. These effects were associated with activation of the Sirt/NF-κB pathway.
Authors
- Dawei Ran (ORCID: https://orcid.org/0000-0003-1060-1769)
- Shizhe Deng
- Jiaxiao Zhou (ORCID: https://orcid.org/0000-0003-0561-0548)
- Yuzheng Du
- Xinming Yang
- Yu Wang
- Lei Shi
- Menghan Li
- Yi Shu
Institutions
- First Teaching Hospital of Tianjin University of Traditional Chinese Medicine (CN)
- Shenzhen Bao'an District People's Hospital (CN)
- CM Hospital (KR)
Publication Details
- Journal
- Acupuncture in Medicine
- Published
- 2026-03-02
- DOI
- https://doi.org/10.1177/09645284261423203
- Primary Topic
- Tryptophan and brain disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00