Quantification of fractional tumor burden for the early detection of post-treatment glioblastoma progression
Follow-up of patients with glioblastoma is complicated by the similar appearance of treatment effects and tumor growth on MRI. Perfusion imaging provides a basis for the creation of FTB maps. These visualize the heterogeneity of brain lesions. Quantitative analysis of FTB maps can help differentiate tumor growth from treatment effect with reasonable accuracy.
Authors
- Anja G. van der Kolk (ORCID: https://orcid.org/0000-0002-8267-8848)
- Manoj Mannil (ORCID: https://orcid.org/0000-0001-9335-9546)
- Tom W. J. Scheenen (ORCID: https://orcid.org/0000-0002-4468-1480)
- Rik van den Elshout (ORCID: https://orcid.org/0000-0002-8765-3017)
- Anne I.J. Arens (ORCID: https://orcid.org/0000-0001-7066-5372)
- Siem D. A. Herings (ORCID: https://orcid.org/0000-0003-4791-5681)
- Rebecca de Wit
- Dylan Henssen
- Baris Saglik
Institutions
- Radboud University Nijmegen (NL)
- Radboud University Medical Center (NL)
- Radboud Institute for Molecular Life Sciences (NL)
Publication Details
- Journal
- European Radiology Experimental
- Published
- 2026-03-02
- DOI
- https://doi.org/10.1186/s41747-026-00685-3
- Primary Topic
- Glioma Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00