Characteristics of adverse reactions to kratom and implementation of harm reduction strategies in a sample of ethnobotanical tea bar patrons in Colorado

Adverse reactions to kratom may be associated with certain contextual factors. Several techniques are reportedly used to mitigate adverse reactions, but the efficacy of these techniques is unknown. More data are needed to understand the causes and consequences of adverse reactions to kratom, and to better understand potential harm reduction strategies for reducing adverse experiences. More research could also shed light on the extent to which kratom serving size and various product formulations (e.g. whole leaf vs. extracts) are predictive of adverse effects.

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Publication Details

Journal
Harm Reduction Journal
Published
2026-03-02
DOI
https://doi.org/10.1186/s12954-025-01382-x
Primary Topic
Alkaloids: synthesis and pharmacology
Type
article
Field-Weighted Citation Impact
0.00
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article

Characteristics of adverse reactions to kratom and implementation of harm reduction strategies in a sample of ethnobotanical tea bar patrons in Colorado

Cianna J Piercey, Hollis C. Karoly, Devin Henry, Joseph Cameron et al.
Harm Reduction Journal
Alkaloids: synthesis and pharmacology
article

Characteristics of adverse reactions to kratom and implementation of harm reduction strategies in a sample of ethnobotanical tea bar patrons in Colorado

Cianna J Piercey, Hollis C. Karoly, Devin Henry, Joseph Cameron, Carter Bruning, Jesse Ruehrmund, Katelyn Weldon, Isabella Packwood, Kirsten E. Smith, Riley Ahern
article en

Abstract

Adverse reactions to kratom may be associated with certain contextual factors. Several techniques are reportedly used to mitigate adverse reactions, but the efficacy of these techniques is unknown. More data are needed to understand the causes and consequences of adverse reactions to kratom, and to better understand potential harm reduction strategies for reducing adverse experiences. More research could also shed light on the extent to which kratom serving size and various product formulations (e.g. whole leaf vs. extracts) are predictive of adverse effects.

Harm Reduction Journal
Johns Hopkins University (US), Brown University (US), Johns Hopkins Medicine (US), Behavioral Pharma (United States) (US), University of Colorado Anschutz Medical Campus (US), Columbia University (US), Colorado State University (US)
Openalex Percentile: Top 35%
Alkaloids: synthesis and pharmacology
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