Heterogeneity of Treatment Effects of Glucagon-Like Peptide-1 Receptor Agonists for Weight Loss in Adults
In this systematic review and meta-analysis, GLP-1 RAs produced greater weight loss among women than men; however, their efficacy was consistent across other important subpopulations. These findings may inform clinical decision-making.
Authors
- Sydney V. Lewis (ORCID: https://orcid.org/0000-0003-4489-3982)
- Minji Kim (ORCID: https://orcid.org/0000-0003-3340-8603)
- Ian J. Saldanha
- Hemalkumar B. Mehta
- Sophie Dilek
- G. Caleb Alexander
- Xuya Xiao
- Dami Bolanle
- Qilin Deng
Institutions
- Johns Hopkins University (US)
- Johns Hopkins Medicine (US)
Publication Details
- Journal
- JAMA Internal Medicine
- Published
- 2026-03-02
- DOI
- https://doi.org/10.1001/jamainternmed.2025.8222
- Primary Topic
- Diabetes Treatment and Management
- Type
- article
- Field-Weighted Citation Impact
- 0.00