Surgical removal of visceral adipose tissue has therapeutic benefit in male APPNL-F mice
Sex-specific differences in glucose and lipid metabolism and lipid accumulation underlie the divergent responses to VFR in APP<sup>NL-F</sup> mice, with symptomatic males showing the only beneficial outcomes in metabolism and cognition.
Authors
- Kathleen Quinn
- Yimin Fang
- Samuel McFadden (ORCID: https://orcid.org/0000-0002-2289-5066)
- Mackenzie R. Peck
- Jenelle E. Chapman
- Tiarra Hill
- Erin R Hascup
- Kevin N. Hascup
- Andrzej Bartke
Institutions
- Southern Illinois University School of Medicine (US)
- Alzheimer’s Disease Neuroimaging Initiative (US)
Publication Details
- Journal
- Frontiers in Endocrinology
- Published
- 2026-03-02
- DOI
- https://doi.org/10.3389/fendo.2026.1681801
- Primary Topic
- Mesenchymal stem cell research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Institutes of Health
- National Institute on Aging