Prognostic stratification with composite insulin resistance–inflammation biomarkers in patients with chronic kidney disease and coronary artery disease across glycemic statuses
Composite biomarkers integrating IR and inflammation, particularly CTI, significantly enhance mortality prediction in patients with CKD and CAD. The predictive utility is modulated by underlying glycemic status, enabling refined risk stratification and potentially guiding tailored management strategies for this complex patient population.
Authors
- Enmin Xie (ORCID: https://orcid.org/0000-0002-0767-7407)
- R U I Zhang
- Zixiang Ye
- Chao Wu (ORCID: https://orcid.org/0000-0003-3194-6969)
- Chenxi Song
- Kefei Dou
- Haoyu Wang
Institutions
- Chinese Center For Disease Control and Prevention (CN)
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Fu Wai Hospital (CN)
Publication Details
- Journal
- Cardiovascular Diabetology
- Published
- 2026-03-02
- DOI
- https://doi.org/10.1186/s12933-026-03108-0
- Primary Topic
- Adipokines, Inflammation, and Metabolic Diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.00