Human umbilical cord mesenchymal stem cells therapy for Alzheimer’s disease: a systematic review and meta-analysis of mouse models
Human umbilical cord mesenchymal stem cells can improve behavioral and pathological outcomes in AD mouse models via multiple mechanisms of action. The intravenous route using medium to high doses emerges as a critical factor for achieving optimal effects, providing important evidence and informing future experimental design and clinical translational research.
Authors
- Ya Shao
- Hua Cao
- Jianping Zhang
- Wei Ding
- Chunyan Si
- Yunxia Tian
- Liang Ma
- Zhiqiang Fan
Institutions
- Gansu Provincial Hospital (CN)
Publication Details
- Journal
- Frontiers in Neurology
- Published
- 2026-03-02
- DOI
- https://doi.org/10.3389/fneur.2026.1783757
- Primary Topic
- Mesenchymal stem cell research
- Type
- article
- Field-Weighted Citation Impact
- 0.00