CSWin-MDKDNet: cross-shaped window network with multi-dimensional fusion and knowledge distillation for medical image segmentation

In recent years, deep learning has achieved significant advancements in medical image segmentation. Medical image segmentation is fundamental to computer-aided diagnosis, yet challenges persist in balancing local detail preservation and global context modeling. This paper proposes CSWin-MDKDNet, a novel Transformer-based architecture enhanced with Multi-dimensional Selective Fusion (MDSF) and Knowledge Distillation Loss (KD-loss). The MDSF module refines multi-scale feature fusion through channel-spatial attention, while KD-loss mitigates feature redundancy in deep layers. Evaluated on the Synapse (multi-organ CT), ACDC(cardiac MRI) and ISIC2018 datasets, our model achieves state-of-the-art performance, with 81.82% DSC (Synapse), 91.76% DSC (ACDC) and 91.64% DSC(ISIC2018), outperforming existing methods in accuracy.

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Publication Details

Journal
Scientific Reports
Published
2026-03-02
DOI
https://doi.org/10.1038/s41598-026-40690-5
Primary Topic
Advanced Neural Network Applications
Type
article
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article

CSWin-MDKDNet: cross-shaped window network with multi-dimensional fusion and knowledge distillation for medical image segmentation

Quan Lan, Chenhui Yang, Jiangzhou Lin, Hua Peng et al.
Scientific Reports
Advanced Neural Network Applications
article

CSWin-MDKDNet: cross-shaped window network with multi-dimensional fusion and knowledge distillation for medical image segmentation

Quan Lan, Chenhui Yang, Jiangzhou Lin, Hua Peng, L J Sun, ShiHao Cai, Hongbin Lin, Haiyue Bao, Guanqing Cui
article en

Abstract

In recent years, deep learning has achieved significant advancements in medical image segmentation. Medical image segmentation is fundamental to computer-aided diagnosis, yet challenges persist in balancing local detail preservation and global context modeling. This paper proposes CSWin-MDKDNet, a novel Transformer-based architecture enhanced with Multi-dimensional Selective Fusion (MDSF) and Knowledge Distillation Loss (KD-loss). The MDSF module refines multi-scale feature fusion through channel-spatial attention, while KD-loss mitigates feature redundancy in deep layers. Evaluated on the Synapse (multi-organ CT), ACDC(cardiac MRI) and ISIC2018 datasets, our model achieves state-of-the-art performance, with 81.82% DSC (Synapse), 91.76% DSC (ACDC) and 91.64% DSC(ISIC2018), outperforming existing methods in accuracy.

Scientific Reports
Xiamen University (CN), First Affiliated Hospital of Xiamen University (CN), Zhongshan Hospital of Xiamen University (CN)
Sustainable cities and communities
Openalex Percentile: Top 39%
Advanced Neural Network Applications
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