Correlation between serum prolactin and the systemic immune-inflammation index in diabetic kidney disease: a cross-sectional study
In patients with DKD, serum PRL exhibits an independent, nonlinear association with SII, characterized by a threshold around 282.85 mIU/L. This finding suggests that PRL may be linked to the dysregulated immune-inflammation axis in DKD, warranting further mechanistic and longitudinal investigation.
Authors
- Zhonghao Qin
- Hanjie Yu
- Haichao Wang (ORCID: https://orcid.org/0000-0001-8921-0554)
- Si Tian
- Kaimin Wang
- AI Peng
- L. L. Wang
- Shijie Wu
- Lei Yang
- Yinhui Li
- Minghao Kong
Institutions
- Affiliated Hospital of Guizhou Medical University (CN)
- Shanghai Tenth People's Hospital (CN)
Publication Details
- Journal
- Frontiers in Endocrinology
- Published
- 2026-03-02
- DOI
- https://doi.org/10.3389/fendo.2026.1772810
- Primary Topic
- Chronic Kidney Disease and Diabetes
- Type
- article
- Field-Weighted Citation Impact
- 0.00